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1

Determining DNA supercoiling enthalpy by isothermal titration calorimetry

Xu, Xiaozhou, Zhi, Xiaoduo, Leng, Fenfei

Journal:

Year:

2012

Language:

english

File:

PDF, 688 KB

english, 2012

2

Divide a Plasmid DNA Molecule into Two Independent Superhelical Domains by Sequence-Specific DNA-Binding Proteins: A DNA Superhelical Barrier Model

Leng, Fenfei, Chen, Bo

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 40 KB

english, 2011

3

Fluorescently labeled circular DNA molecules for DNA topology and topoisomerases

Gu, Maxwell, Berrido, Andrea, Gonzalez, Walter G., Miksovska, Jaroslava, Chambers, Jeremy W., Leng, Fenfei

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.10 MB

english, 2016

4

Cations Form Sequence Selective Motifs within DNA Grooves via a Combination of Cation-Pi and Ion-Dipole/Hydrogen Bond Interactions

Stewart, Mikaela, Dunlap, Tori, Dourlain, Elizabeth, Grant, Bryce, McFail-Isom, Lori, Leng, Fenfei

Journal:

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

5

Peptide Sequence Influence on the Conformational Dynamics and DNA binding of the Intrinsically Disordered AT-Hook 3 Peptide

Garabedian, Alyssa, Bolufer, Alexander, Leng, Fenfei, Fernandez-Lima, Francisco

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.39 MB

english, 2018

6

Identification of Suramin as a Potent and Specific Inhibitor of the Mammalian High Mobility Group Protein at-Hook 2 (HMGA2)-DNA Interactions

Su, Linjia, Vasile, Steve, Smith, Layton, Leng, Fenfei

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 42 KB

english, 2018

7

Daunomycin disrupts nuclear assembly and the coordinate initiation of DNA replication in Xenopus egg extracts

Fenfei Leng, Gregory H. Leno

Journal:

Journal of Cellular Biochemistry

Year:

1997

Language:

english

File:

PDF, 308 KB

english, 1997

8

Inhibition of high-mobility-group A2 protein binding to DNA by netropsin: A biosensor-surface plasmon resonance assay

Yi Miao, Tengjiao Cui, Fenfei Leng, W. David Wilson

Journal:

Analytical Biochemistry

Year:

2008

Language:

english

File:

PDF, 519 KB

english, 2008

9

Chemical cross-linking of ethidium to DNA by glyoxal

Fenfei Leng, David Graves, Jonathan B. Chaires

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1998

Language:

english

File:

PDF, 299 KB

english, 1998

10

Energetics of Binding the Mammalian High Mobility Group Protein HMGA2 to poly(dA-dT)2 and poly(dA)-poly(dT)

Tengjiao Cui, Shuo Wei, Keith Brew, Fenfei Leng

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 430 KB

english, 2005

11

Transcription-coupled Hypernegative Supercoiling of Plasmid DNA by T7 RNA Polymerase in Escherichia coli Topoisomerase I-Deficient Strains

Rebecca Samul, Fenfei Leng

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 627 KB

english, 2007

12

A rapid procedure to purify Escherichia coli DNA topoisomerase I

Xiaozhou Xu, Fenfei Leng

Journal:

Protein Expression and Purification

Year:

2011

Language:

english

File:

PDF, 591 KB

english, 2011

13

Binding the Mammalian High Mobility Group Protein AT-hook 2 to AT-Rich Deoxyoligonucleotides: Enthalpy-Entropy Compensation

Joynt, Suzanne, Morillo, Victor, Leng, Fenfei

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 405 KB

english, 2009

14

Dependence of transcription-coupled DNA supercoiling on promoter strength in Escherichia coli topoisomerase I deficient strains

Xiaoduo Zhi, Fenfei Leng

Journal:

Year:

2013

Language:

english

File:

PDF, 870 KB

english, 2013

15

Base Specific and Regioselective Chemical Cross-Linking of Daunorubicin to DNA

Leng, Fenfei, Savkur, Rajesh, Fokt, Izabela, Przewloka, Teresa, Priebe, Waldemar, Chaires, Jonathan B.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 337 KB

english, 1996

16

Ultratight DNA Binding of a New Bisintercalating Anthracycline Antibiotic †

Leng, Fenfei, Priebe, Waldemar, Chaires, Jonathan B.

Journal:

Year:

1998

Language:

english

File:

PDF, 131 KB

english, 1998

17

Transcription-coupled DNA supercoiling in defined protein systems and in E. coli topA mutant strains

Fulcrand, Geraldine, Zhi, Xiaoduo, Leng, Fenfei

Journal:

Year:

2013

Language:

english

File:

PDF, 601 KB

english, 2013

18

Lactose Repressor Functions as a DNA Topological Barrier in Escherichia Coli Lactose Operon

Fulcrand, Geraldine, Eichelbaum, Steven, Leng, Fenfei

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 70 KB

english, 2013

19

Protein-Induced DNA Unwinding is An Intrinsic Feature of Certain Sequence-Specific DNA-Binding Proteins

Leng, Fenfei, Chen, Bo

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 41 KB

english, 2009

20

Activating the Prokaryotic leu-500 Promoter by Transient, Dynamic DNA Supercoiling in Escherichia Coli

Zhi, Xiaoduo, Perez, Catherine, Dages, Samantha, Dages, Kelley, Eichelbaum, Steve, Makemson, John, Leng, Fenfei

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 135 KB

english, 2014

21

Biochemical and Biophysical Properties of Positively Supercoiled DNA

Berrido, Andrea M., Chen, Andrew, Tse-Dinh, Yuk-Ching, Leng, Fenfei

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 63 KB

english, 2014

22

DNA Bending by the Mammalian High-Mobility Group Protein AT Hook 2

Chen, Bo, Young, Jasmine, Leng, Fenfei

Journal:

Year:

2010

Language:

english

File:

PDF, 2.71 MB

english, 2010

23

Specific Recognition of AT-Rich DNA Sequences by the Mammalian High Mobility Group Protein AT-hook 2: A SELEX Study †

Cui, Tengjiao, Leng, Fenfei

Journal:

Year:

2007

Language:

english

File:

PDF, 313 KB

english, 2007

24

Structure-Based Design of a New Bisintercalating Anthracycline Antibiotic

Chaires, Jonathan B., Leng, Fenfei, Przewloka, Teresa, Fokt, Izabela, Ling, Yi-He, Perez-Soler, Roman, Priebe, Waldemar

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 165 KB

english, 1997

25

Structure of a DNA−Bisdaunomycin Complex †,‡

Hu, Gary G., Shui, Xiuqi, Leng, Fenfei, Priebe, Waldemar, Chaires, Jonathan B., Williams, Loren Dean

Journal:

Year:

1997

Language:

english

File:

PDF, 293 KB

english, 1997

26

Isomerization Kinetics of AT Hook Decapeptide Solution Structures

Schenk, Emily R., Ridgeway, Mark E., Park, Melvin A., Leng, Fenfei, Fernandez-Lima, Francisco

Journal:

Analytical Chemistry

Year:

2014

Language:

english

File:

PDF, 1.75 MB

english, 2014

27

Selective inhibition of bacterial topoisomerase I by alkynyl-bisbenzimidazoles

Ranjan, Nihar, Fulcrand, Geraldine, King, Ada, Brown, Joseph, Jiang, Xiuping, Leng, Fenfei, Arya, Dev P.

Journal:

Year:

2014

Language:

english

File:

PDF, 534 KB

english, 2014

28

Involvement of Escherichia coli DNA Replication Proteins in Phage Lambda Red-Mediated Homologous Recombination

Poteete, Anthony R., Leng, Fenfei

Journal:

Year:

2013

Language:

english

File:

PDF, 225 KB

english, 2013

29

Large Scale Preparation of the Mammalian High Mobility Group Protein A2 for Biophysical Studies

Cui, Tengjiao, Joynt, Suzanne, Morillo, Victor, Baez, Maria, Hua, Zhichun, Wang, Xiaotang, Leng, Fenfei

Journal:

Protein & Peptide Letters

Year:

2007

Language:

english

File:

PDF, 208 KB

english, 2007

30

Characterization of an epoxide hydrolase from the Florida red tide dinoflagellate, Karenia brevis

Sun, Pengfei, Leeson, Cristian, Zhi, Xiaoduo, Leng, Fenfei, Pierce, Richard H., Henry, Michael S., Rein, Kathleen S.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.67 MB

english, 2015

31

Dividing a supercoiled DNA molecule into two independent topological domains

Fenfei Leng, Bo Chen and David D. Dunlap

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.71 MB

english, 2011

32

Design and Construct a Type of Fluorescently Labeled Circular DNA Molecules to Study DNA Topology and Topoisomerases by Fluorescence Resonance Energy Transfer (FRET)

De Cabrera, Maria, Gu, Maxwell, Leng, Fenfei

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 42 KB

english, 2016

33

HU Protein and DNA Supercoiling Dramatically Enhance Lac-Repressor-Mediated DNA Looping

Yan, Yan, Leng, Fenfei, Dunlap, David D., Finzi, Laura

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 41 KB

english, 2016

34

Effect of FIS on Transcription-Coupled DNA Supercoiling in E. coli

Dages, Samantha, Zhi, Xiaoduo, Leng, Fenfei

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 60 KB

english, 2016

35

Protein-induced DNA linking number change by sequence-specific DNA binding proteins and its biological effects

Journal:

Biophysical Reviews

Year:

2016

Language:

english

File:

PDF, 1.42 MB

english, 2016

36

Direct observation of a 91 bp LacI-mediated, negatively supercoiled DNA loop by atomic force microscope

Fulcrand, Geraldine, Chapagain, Prem, Dunlap, David, Leng, Fenfei

Journal:

Year:

2016

Language:

english

File:

PDF, 882 KB

english, 2016

37

RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals

Ahmad, Muzammil, Xue, Yutong, Lee, Seung Kyu, Martindale, Jennifer L., Shen, Weiping, Li, Wen, Zou, Sige, Ciaramella, Maria, Debat, Hélène, Nadal, Marc, Leng, Fenfei, Zhang, Hongliang, Wang, Quan, Sia

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 3.87 MB

english, 2016

38

Protein-Mediated Loops in Supercoiled DNA Create Large Topological Domains

Yan, Yan, Dunlap, David D., Leng, Fenfei, Finzi, Laura

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 42 KB

english, 2017

39

Selective Inhibition of E. coli RNA and DNA Topoisomerase I by Hoechst 33258 Derived Mono and Bisbenzimidazoles

Ranjan, Nihar, Story, Sandra, Fulcrand, Geraldine, Leng, Fenfei, Ahmad, Muzammil, King, Ada, Sur, Souvik, Wang, Weidong, Tse-Dinh, Yuk-Ching, Arya, Dev Priya

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.64 MB

english, 2017

40

Protein-induced DNA linking number change by sequence-specific DNA binding proteins and its biological effects

Journal:

Biophysical Reviews

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

41

DNA supercoiling, a critical signal regulating the basal expression of the lac operon in Escherichia coli

Fulcrand, Geraldine, Dages, Samantha, Zhi, Xiaoduo, Chapagain, Prem, Gerstman, Bernard S., Dunlap, David, Leng, Fenfei

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.24 MB

english, 2016

42

Transient and dynamic DNA supercoiling potently stimulates the leu-500 promoter in Escherichia coli

Zhi, Xiaoduo, Dages, Samantha, Dages, Kelley, Liu, Yingting, Hua, Zi-Chun, Makemson, John, Leng, Fenfei

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 506 KB

english, 2017

43

Biochemical and biophysical properties of positively supercoiled DNA

Liu, Yingting, Berrido, Andrea M., Hua, Zi-Chun, Tse-Dinh, Yuk-Ching, Leng, Fenfei

Journal:

Biophysical Chemistry

Year:

2017

Language:

english

File:

PDF, 1.24 MB

english, 2017

44

Protein-mediated looping of DNA under tension requires supercoiling

Yan, Yan, Leng, Fenfei, Finzi, Laura, Dunlap, David

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 2.05 MB

english, 2018

45

Tailoring peptide conformational space with organic gas modifiers in TIMS-MS

Garabedian, Alyssa, Leng, Fenfei, Ridgeway, Mark E., Park, Melvin A., Fernandez-Lima, Francisco

Journal:

International Journal for Ion Mobility Spectrometry

Year:

2018

Language:

english

File:

PDF, 1.45 MB

english, 2018

46

Protein-mediated loops in supercoiled DNA create large topological domains

Yan, Yan, Ding, Yue, Leng, Fenfei, Dunlap, David, Finzi, Laura

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 446 KB

english, 2018

47

Differentiating Parallel and Antiparallel DNA Duplexes in the Gas Phase Using Trapped Ion Mobility Spectrometry

Butcher, David, Chapagain, Prem P., Leng, Fenfei, Fernandez-Lima, Francisco

Journal:

Journal of Physical Chemistry B

Year:

2018

Language:

english

File:

PDF, 851 KB

english, 2018

48

Species-Selective Killing of Bacteria by Antimicrobial Peptide-PNAs

Mondhe, Madhav, Chessher, Ashley, Goh, Shan, Good, Liam, Stach, James E. M., Leng, Fenfei

Journal:

Year:

2014

Language:

english

File:

PDF, 395 KB

english, 2014

49

DNA Metabolism in Balance: Rapid Loss of a RecA-Based Hyperrec Phenotype

Bakhlanova, Irina V., Dudkina, Alexandra V., Wood, Elizabeth A., Lanzov, Vladislav A., Cox, Michael M., Baitin, Dmitry M., Leng, Fenfei

Journal:

Year:

2016

Language:

english

File:

PDF, 2.21 MB

english, 2016

50

Aminoglycosylation Can Enhance the G-Quadruplex Binding Activity of Epigallocatechin

Bai, Li-Ping, Ho, Hing-Man, Ma, Dik-Lung, Yang, Hui, Fu, Wai-Chung, Jiang, Zhi-Hong, Leng, Fenfei

Journal:

Year:

2013

Language:

english

File:

PDF, 619 KB

english, 2013